El presente artículo reconoce que las dos grandes metodologías de Foucault (la arqueología y la genealogía) surgieron en dos momentos diferentes de su enfoque metodológico, y argumenta que a partir de la década del setenta se desarrolla el concepto de dispositivo en el filósofo debido a una discontinuidad en su investigación. Se sostiene que este problema surgió a raíz de una serie de situaciones: el descubrimiento de un nuevo problema de investigación y su relación con la ocurrencia de una coyuntura (...) sociopolítica especifica (fracaso de las movilizaciones sociales del mayo francés en 1968). Lo anterior llevó a Foucault a plantear la pregunta por ¿cómo se ejerce el poder y cuál es su relación con el saber?, en lugar del antiguo interrogante sobre ¿qué es el poder? Esta transformación de la pregunta resultó fundamental en Foucault, ya que le permite concluir que todo dispositivo presupone la existencia de un poder y que todo poder se ejerce mediante la utilización de un saber. El artículo se cierra con una referencia a Jurgen Habermas, autor que precisa la crisis que generó en Foucault el fracaso de las movilizaciones sociales ocurridas durante el denominado mayo francés. El presente trabajo se elaboró a partir de un método de investigación cualitativa y una técnica de rastreo bibliográfico. (shrink)

Background: Serious games have shown positive results in increasing motivation, adherence to treatment and strengthening the therapeutic alliance in multiple psychiatric disorders. In particular, patients with impulse control disorders and other disorders in which the patient suffers from inhibitory control deficits have been shown to benefit from serious games.Aim: The aim of this study was to describe the characteristics and to evaluate the usability of a new serious videogame, e-Estesia. This serious videogame was designed to improve emotion regulation in patients (...) with gambling disorder. Preliminary results from a pilot sample are also reported.Method: A pilot sample of 26 patients undergoing treatment for GD was recruited. Participants used e-Estesia on a tablet, which was connected to a thoracic band that sent heart rate and heart rate variability data to the videogame platform in order to provide biofeedback. The System Usability Scale was completed by patients to determine the usability of e-Estesia.Results and Discussion: e-Estesia performed comparatively well for all the explored groups. Around 84.6% of the patients endorsed that it was easy to use. Female patients with GD presented higher HRV during the use of the serious videogame compared to men. (shrink)

Em “Compreender Hans Jonas”, Jelson Oliveira se propõe a apresentar de maneira clara e objetiva o longo caminho percorrido pelo alemão Hans Jonas em sua jornada filosófica, cujo ápice é a formulação da tão urgente ética da responsabilidade. Por meio de uma ánalise cuidodadosa das obras deixadas por Jonas, Jelson confere inestimável importância a um livro único, que torna prazeroso o conhecimento sobre o desenvolvimento intelectual do filósofo do Princípio Responsabilidade.

Jelson Roberto de Oliveira, autor de “Compreender Hans Jonas”, é graduado em Filosofia pela Universidade Federal do Paraná, com especialização em Sociologia Política e mestrado em História da Filosofia Moderna e Contemporânea pela mesma universidade. Atualmente é professor da pós-graduação em Filosofia na PUC-PR, e coordenador do GT Hans Jonas, da Anpof, que reúne vários pesquisadores de nível nacional na área. Ética para a civilização tecnológica e A solidão como virtude moral em Nietzsche são alguns dos diversos títulos que compõem (...) o acervo de obras do autor. (shrink)

El siguiente artículo se propone la aproximación, desde la filosofía, a uno de los problemas contemporáneos más relevantes de la violencia política: el urbicidio, concepto que señala la destrucción de las ciudades. El análisis desarrollado deconstruye conceptualmente las implicaciones que tienen para los tiempos de globalización bélica y armamentos tecnológicos una serie de prácticas estructuradas, consensuadas y abiertamente aceptadas que, bajo los neologismos de renovación, modernidad y progreso aniquila las formas de habitar de una comunidad históricamente articulada, en la íntima (...) relación de los habitantes con una ciudad determinada. Este trabajo responde a la siguiente pregunta: ¿qué se acaba o qué se pierde cuando se destruye una ciudad? Esto es lo que el urbicidio nos permite comprender desde el enfoque filosófico en acercamientos categoriales como son el espacio, el cuerpo y el habitar, e irradia hacia temas de comprensión ontológica, cultural, política, social y ética. (shrink)

El objetivo principal es propiciar la reflexión acerca de las premisas sobre las que se asienta nuestra asimilada centralización del “trabajo” en nuestras vidas. El trabajo a menudo transcurre por encima de otros aspectos también significativos. La reflexión será guiada, entre otros, a través de la estimulante lectura de la obra de Bauman Trabajo, consumismo y nuevos pobres. Los ejes de reflexión son dos. En primer lugar, comparar históricamente la perspectiva sobre la concepción del trabajador industrial con la perspectiva sobre (...) el trabajador contemporáneo y desde su propia autocomprensión: parece que hayamos asimilado el “vivir para trabajar” y descartado el “trabajar para vivir”. Esta comparación es pertinente, aunque hoy predomine un paradigma novedoso de flexibilidad que, en ausencia de un compromiso duradero con un trabajo, genera una nueva aproximación a nuestra autoconcepción. Por tanto, ¿qué marco de interpretación tenemos para concebimos a nosotros mismos? En segundo lugar, como consecuencia del primer análisis: si el trabajo y sus exigencias ocupan la mayor parte de nuestro tiempo, es probable que haya consecuencias a nivel antropológico. ¿Qué pasa con el resto de actividades humanas o de bienes –la amistad, la familia, el conocimiento, etc.– que necesitan ser cultivados también para adquirir una vida desarrollada? (shrink)

Using the Self-Determination Theory as a framework, this study tests the predictive capacity of the teacher’s interpersonal style of autonomy support at a higher education institution, and the grit on the satisfaction of basic psychological needs, intrinsic motivation, group cohesion, and life satisfaction in university students. A sample composed of 489 Colombian university students, aged between 18 and 41 years, was used; they filled in the questionnaires that measured the variables of interest. After the analysis of structural equations, the results (...) showed that the perception of teaching style of autonomy support and the grit positively predicted the basic psychological needs and these predicted the intrinsic motivation, which in turn predicted group cohesion and satisfaction with life. The model describes the possible importance of promoting the teacher’s interpersonal style of autonomy support within the university setting in the search for satisfaction with life along with the active role of the student through the mediation of the satisfaction of basic psychological needs, increased quality motivation, and high group cohesion. (shrink)

"El repertorio bibliográfico no presenta resumen".

El Repertorio bibliográfico sobre Martin Heidegger que se presenta a continuación, reúne la información obtenida de las más de 240 revistas de filosofía disponibles en la Hemeroteca de la Pontificia Universidad Católica del Perú. El Repertorio incluye referencias bibliográficas completas de los artículos, reseñas, estudios críticos, traducciones y otros documentos que abordan la obra del importante pensador alemán hasta el año 2010.

This article proposes that the meditation on contemporary violence, in the Eduardo Nicol’s works, is part of a broad process of philosophical reflection of three decades, which questions the present and the future of humanity. Violence, for Nicol, is the display of a special rationality, born in Modernity, which he calls “force majeure reason” (razón de fuerza mayor) that is a change of life regime in the contemporary human being, sometimes to the basic need for survival, utility and a (...) network of forcedness that reduces possibilities and freedom. In this way, the article traces in Nicol´s work the conformation —from the notion, to the idea and the conceptual framework— of violence as a disposition, act and system. Political regulation, hate and intersubjective violence, hostility and war in a global world are the focus of this collaboration. Este artículo propone que la meditación sobre la violencia contemporánea, en la obra de Eduardo Nicol, está inscrita en un amplio proceso de reflexión filosófica de tres décadas, que interroga sobre el presente y el porvenir de la humanidad. La violencia, para Nicol, es el despliegue de una racionalidad peculiar —gestada en la Modernidad— por disolvente de la verdad, a la cual él llama “razón de fuerza mayor”. De este modo, el artículo rastrea en la obra de este filósofo la conformación —desde la noción, hasta la idea y marco conceptual— de la violencia en tanto disposición, acto y sistema. La regulación política, el odio y la violencia intersubjetiva, la hostilidad y la guerra en un mundo global son el foco de atención de este artículo. (shrink)

Darwin in Argentina -- Conflicting Systems -- Francisco Javier Muniz (1795-1871) -- Hermann Burmeister (1807-1891) -- Francisco P. Moreno (1852-1919) -- Domingo F. Sarmiento (1811-1888) -- Eduardo Holmberg (1852-1937) -- Florentino Ameghino (1854-1911) -- Jose Ingenieros (1877-1925) -- Carlos Octavio Bunge (1875-1918).

In diesem Buch geht es um die faszinierende Fähigkeit der menschlichen Sprache, mit Hilfe winziger (mikrosemantischer) Morpheme als Hilfsmittel komplizierte logische (mathematische) Bedeutungen auszudrücken. Sprachen markieren Bedeutungen mit identischen Schlussfolgerungen, indem sie identische Partikel verwenden, und diese Partikel schleichen sich so in eine Vielzahl von Ausdrücken ein. Aufgrund ihrer Multitasking-Fähigkeit, scheinbar disparate Bedeutungen auszudrücken, werden sie als Superpartikel bezeichnet. Diese Partikel sind perfekte Fenster in die Verzahnung mehrerer grammatischerModule und die Art der Interaktion dieser Module im Laufe der Zeit. Fest (...) verankert in dem Modul, in dem die grammatischen Knochen gebaut und zusammengesetzt werden (enge Morphosyntax), erhalten Superpartikel je nach der Struktur, in der sie vorkommen, unterschiedliche Interpretationen (im begrifflich-intentionalen Modul - Semantik). Darüber hinaus sind einige der Interpretationen, die diese Partikel auslösen, inferentiell und gehören nach der Standardrechnung in den Bereich der Pragmatik. Wie können solch winzige Partikel, die selten länger als eine Silbe sind, so mächtige und übergreifende Wirkungen im intermodularen grammatischen Raum haben? Dies ist der platonische Hintergrund, vor dem dieses Buch steht. Dieses Buch ist eine Übersetzung einer englischen Originalausgabe. Die Übersetzung wurde mit Hilfe von künstlicher Intelligenz (maschinelle Übersetzung durch den Dienst DeepL.com) erstellt. Eine anschließende menschliche Überarbeitung erfolgte vor allem in Bezug auf den Inhalt, so dass sich das Buch stilistisch anders liest als eine herkömmliche Übersetzung. (shrink)

Background: Eye movement desensitization and reprocessing [EMDR] is an innovative, evidence-based and effective psychotherapy for post-traumatic stress disorder [PTSD]. As with other psychotherapies, the effectiveness of EMDR contrasts with a limited knowledge of its underlying mechanism of action. In its relatively short life as a therapeutic option, EMDR has not been without controversy, in particular regarding the role of the bilateral stimulation as an active component of the therapy. The high prevalence of EMDR in clinical practice and the dramatic increase (...) in EMDR research in recent years, with more than 26 randomized controlled trials published to date, highlight the need for a better understanding of its mechanism of action. Methods: We conducted a thorough systematic search of studies published until October 2017, using PubMed, ScienceDirect, Web of Knowledge and Scopus databases that examined the mechanism of action of EMDR or provided conclusions within the framework of current theoretical models of EMDR functioning. Results: Seventy-five studies were selected for review and classified into three overarching models; (i) psychological models (ii) psychophysiological models and (iii) neurobiological models. The evidence available from each study was analysed and discussed. Results demonstrated a reasonable empirical support for the working memory hypothesis and for the physiological changes associated with successful EMDR therapy. Recently, more sophisticated structural and functional neuroimaging studies using high resolution structural and temporal techniques are starting to provide preliminary evidence into the neuronal correlates before, during and after EMDR therapy. Discussion: Despite the increasing number of studies that published in recent years, the research into the mechanisms underlying EDMR therapy are still in its infancy. Studies in well-defined clinical and non-clinical populations, larger sample sizes and tighter methodological control are further needed in order to establish firm conclusions. (shrink)

Pragmatics is the theory of conversation; more specifically, pragmatics is the discipline that studies linguistic rationality. This concept has to be interpreted as the instrumental coherence betweencommunicative goals and means. Therefore, pragmatics is essentially about the relations of relevance between utterances and contexts, understanding these as sets of beliefs held by the speaker and eventually shared by the hearer, and not as the set of objective features surrounding communicative interaction.

This paper defends the Quine-Putnam mathematical indispensability argument against two objections raised by Penelope Maddy. The objections concern scientific practices regarding the development of the atomic theory and the role of applied mathematics in the continuum and infinity. I present two alternative accounts by Stephen Brush and Alan Chalmers on the atomic theory. I argue that these two theories are consistent with Quine’s theory of scientific confirmation. I advance some novel versions of the indispensability argument. I argue that these new (...) versions accommodate Maddy’s history of the atomic theory. Counter-examples are provided regarding the role of the mathematical continuum and mathematical infinity in science. (shrink)

During the last decades the question of defining life has gained increased interest but, at the same time, the difficulty in reaching consensus on a possible answer has led many to skeptical positions. This, in turn, has raised a wider debate about why defining life is so hard and controversial. Such a debate introduces additional aspects to be considered, like the role and nature of a definition of life itself. In this paper, we will focus on those aspects, arguing that (...) progress can be made if we conceive definitions of life as open heuristic tools that contribute to develop specific research strategies in the biological sciences and, more generally, to increase our understanding of life’s complexity. In contrast with pragmatic or operationalist approaches, we will defend that definitions of life comprise a set of ontological assumptions, together with an inherent unifying vocation, so they should be subject to comparison and critical assessment, closely related to the success or failure of the corresponding research programs, but also to the success or failure in establishing well-grounded interconnections among the latter. We consider that the search for a more coherent, integrated and generalized theory of biology cannot be pursued without keeping an empirical standpoint, and the exercise of defining life should not be taken as an obstacle but as a valuable instrument to achieve that goal. (shrink)

Esta investigación se emprende motivada por la necesidad de desentrañar la progresión delos modelos de aprendizaje, los cuales se han ido adaptando para responder a las demandas de lasociedad en su dinámica constante de fluctuación y transformaciones. El objetivo de este trabajo es examinar de forma sistemática la evolución de los modelos de aprendizaje, destacando los cambios paradigmáticos que han favorecido la transición de enfoques de aprendizaje tradicionales hacia propuestas más innovadoras y transdisciplinarias. Para lograrlo, se lleva a cabo un (...) análisis bibliográfico apoyado en el método hermenéutico para la interpretación contextual de la literatura y los discursos, a fin de desentrañar las complejidades inherentes en la evolución de los modelos de aprendizaje. Los resultados resaltan la influencia limitante del paradigma de la simplicidad en laformación educativa tradicional y la necesidad de un giro hacia la dialogicidad y la colaboración eintegración disciplinaria para avanzar hacia la complejidad. Se concluye argumentando a favor de la adopción del paradigma de la complejidad, abogando por una epistemología transdisciplinariay un enfoque de aprendizaje interestructurante, que permitan el desarrollo humano integral.El reconocimiento de la complejidad humana en la enseñanza y el aprendizaje exige una transformación radical de la educación hacia prácticas más holísticas y transformadoras, esenciales para construir una sociedad equitativa y justa. (shrink)

In the Work that she presented at the 40th Annual Meeting of the Society for the Advancement of American Philosophy, 7 March 2013, in Galloway, New Jersey, Sassen most tellingly began her keynote with a reflection on method. She spoke of “Before Method.” She spoke of the need to step back, and suspend our extant methods. Emergent social orders, or what she called, in her massive and transformational text Territory, Authority, Rights: From Medieval to Global Assemblages, the emergence of new (...) assemblages, requires that we rethink our old categories, or that we try to assess their usefulness or allow ourselves to countenance their obsolescence. The “before method,” and the invitation to step back, to bracket, or to .. (shrink)

A interação entre o direito, filosofia, filologia, história e literatura, proporcionou ao pensamento de Giambattista Vico (1668-1744) o trânsito nas várias disciplinas do conhecimento humano. Nessa articulação multidisciplinar na qual buscava traçar a genealogia da sociabilidade humana, a figura de Homero é destacada pelo autor ao identificar nos poemas homéricos os dois grandes tesouros da gentilidade. No seu opus magnum, a Scienza Nuova, dedica ao terceiro livro ''Sulla discoverta del Vero Omero'' uma análise detalhada acerca dos poemas homéricos e sua (...) relação com as etapas do desenvolvimento do mundo grego, onde busca objetos que comprovem a veracidade histórica de Homero assim como de seus escritos. Portanto, a finalidade deste artigo é descrever o percurso argumentativo usado por Vico para investigar o poeta grego e seus poemas épicos. (shrink)

A pesquisa analisou os possíveis impactos da aplicação de uma sequência didática envolvendo o aplicativo (app) Telegram à prática pedagógica sob a perspectiva da aprendizagem significativa. Este estudo foi desenvolvido no Mestrado Profissional em Educação Profissional e Tecnológica (ProfEPT) em sua linha de pesquisa “Práticas Educativas em Educação Profissional e Tecnológica (EPT). Nesse estudo aplicado de abordagem qualitativa aplicaram-se dois questionários semiestruturados: um aos estudantes da disciplina de empreendedorismo e outro aos docentes do Curso Técnico em Administração no CEDUP Guaramirim. (...) Complementarmente, optou-se para análise dos dados a análise textual discursiva (ATD), categorizando-os pelos conteúdos, procedimentos e atitudes relevantes à prática pedagógica. Ao consolidar os dados, questionou-se: Como o app Telegram pode ser envolvido à prática pedagógica de forma que contribua para uma aprendizagem significativa? Em resposta a indagação, elaborou-se um produto educacional no formato de uma sequência didática, como instrumento que integrou os conhecimentos prévios aos interesses pedagógicos dos discentes, com os desafios e competências docentes envolvendo a TDIC. Os resultados obtidos demonstraram que a participação discente ao incorporar o app Telegram no processo de planejamento e aplicação da prática pedagógica contribuiu para uma aprendizagem democrática, autônoma, criativa e significativa. (shrink)

The concept of corporate social responsibility (CSR) is not new. Many entrepreneurs created and developed companies along the time, with a strong sense of ethical and social responsibility. This article presents an example of how CSR was conceived and put into practice when Caja de Pensiones para la Vejez y de Ahorros was created in Barcelona in 1905, following the life and ideas of its founder, Francesc Moragas, a lawyer with a deep commitment for social action and a successful conception (...) of the technical and economic dimensions of a financial and social institution. (shrink)

We respond to criticism of our paper “Paradox in Wave-Particle Duality for Non-Perturbative Measurements”. We disagree with Steuernagel’s derivation of the visibility of the Afshar experiment. To calculate the fringe visibility, Steuernagel utilizes two different experimental situations, i.e. the wire grid in the pattern minima and in the pattern maxima. In our assessment, this procedure cannot lead to the correct result for the complementarity properties of a wave-particle in one particular experimental set-up.

O presente estudo tem por objetivo contribuir para o projeto de reatualização da Filosofia do Direito hegeliana inaugurado por Axel Honneth, mas de um modo indireto: meu interesse aqui não é investigar tópicos específicos da Filosofia do Direito, nem mesmo examinar a teoria do reconhecimento como proposta por Honneth, mas iniciar uma caminhada no sentido de tornar explícitos os pressupostos ontológicos carregados por tal projeto de reatualização.

Radical enactivism supports radical embodied cognition (REC), which is the idea that basic or fundamental cognition (perception and action) does not need to be understood in representational, contentful terms. REC departs from the idea that the mind can be naturalized through biological functions, but rejects the idea that mental content, which is understood as having a representational nature, can be naturalized. For REC, the natural origins of content (or NOC) is a program based on the following hypothesis: first, we depart (...) from basic cognitive processes that are target-based and guided by an Ur-intentionality or directedness toward the world, and then sociality enters in the picture when language appears into the scene, allowing for establishing full-blown semantic content in which that content is about worldly states of affairs. Here, we are going to focus on the phenomenon of directedness since there are blind spots in this picture: as many authors claim, REC takes Ur-intentionality as the starting point, but there is simply no explanation to date of how this directedness or Ur-intentionality is established. Therefore, how could we account for Ur-intentionality? How does this kind of intentionality emerge? We believe that we can answer this question if we invoke the best scientific evidence from ecological perceptual learning especially in regard to the role of the environment and the information for perceiving affordances in our learning processes. This allows us to offer an answer to the question of how the most basic form of cognition (Ur-intentionality or directedness) emerges in nature. (shrink)

Este trabajo presenta una interpretación fenomenológico-hermenéutica de la lectura heideggeriana del primer estásimo de la Antígona de Sófocles a través de su lectura de Hölderlin. Nos centraremos en uno de sus aspectos fundamentales que Heidegger expresa con la sentencia: la esencia del hombre es lo inquietante o inhóspito (das Unheimliche, traslación de Heidegger de la voz griega tò deinón). Este aspecto constituye el núcleo fenomenológico del problema del Heimischwerden (el regreso a casa). Nuestro objetivo será mostrar que el sentido de (...) la sentencia solo es sostenible en nuestra situación histórica, de modo que no tiene alcance ahistórico o supra-histórico. Con ello pretendemos ofrecer una hermenéutica del aspecto fenomenológico expresado con la palabra das Heimischwerden que conduzca a pensar en qué consiste el irremediable vínculo con lo familiar, lo doméstico, cuando nuestro mundo histórico es el de la ausencia de contenidos de antemano vinculantes. (shrink)

El artículo explora el proceso de transnacionalización de la política migratoria y la incidencia que ha tenido la emergente perspectiva de la gobernabilidad migratoria en el desarrollo de la “nueva política migratoria” en la Argentina. Se sostiene que su adopción en los organismos del Estado especializados en la migración ha sido decisiva para la configuración de ciertos cambios en los modos de pensar y actuar sobre la llamada “inmigración irregular”. Se propone la noción de políticas de “control con rostro humano” (...) para dilucidar nuevas formas de control de las migraciones y las fronteras internacionales. A través del análisis del concepto de migración ordenada, ingresada al ámbito de gobierno de la migración con la emergencia de un nuevo régimen global de control, se pretende contribuir a la comprensión del origen y fundamento de algunos desplazamientos en las formas de pensar y ejercer el control de las migraciones internacionales en la Argentina actual. (shrink)

Estuda de forma multidisciplinar a bioética e o biodireito, em face dos avanços provocados pela biotecnologia na área jurídica e metajurídica.

Constantine’s adherence to Christianity was a long process conditioned by personal motivations, as well as cultural and political factors. He observed the heathen cults and he did not recognize himself as a christian until the year 314, in his letter to the bishops met in Arelate. Since 324, after the defeat of Licinius, he declared his faith in the One and Only True God in different official texts. He resolved to receive the baptism a few days before his death, in (...) 337, perhaps in the hope of healing fromhis illness. His concept of Christianity was the one of an utilitarian religion, that offered him protection in war and guaranteed his authority in peace with the support of the Church. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:IRBs Under the MicroscopeJonathan D. Moreno (bio)The spring and summer of 1998 were seasons in the sun for institutional review board (IRB) aficionados. Rarely have the arcana of the local human subjects review panels been treated to so much attention in both the executive and the legislative branches of government, not only at the federal but also at the state level. And it looks as if the attention (...) will continue for some time. The spate of interest is due to a series of coincidences: a powerful House of Representatives subcommittee held hearings after its chairman learned about the IRB system during a previous session on research in underdeveloped communities; the Department of Health and Human Services’s Inspector General (DHHS-IG) released a report on IRBs; the National Institutes of Health (NIH) Office of Extramural Research completed a report on clinical trial monitoring; the National Bioethics Advisory Commission (NBAC) readied a report on research involving persons with mental disorders; the states of Maryland and New York completed studies of research with subjects who lack decision-making capacity; and advocacy groups protested a psychiatric research project involving inner city children.Underlying these proximate causes for the IRB blitz is a growing realization that the already considerable clinical trial enterprise will expand significantly over the next few years. Congress is talking about giving the politically popular NIH half again the budget it currently receives, which in turn will stimulate more commercially supported research. The director of the National Cancer Institute is considering a five-fold increase in the number of subjects enrolled in oncology studies over the next several years. Phase I cancer studies are among the most ethically sensitive, so IRBs will have more work cut out for them if this goal is reached. Adding to the rush of interest in IRBs are the government’s recent apology to the survivors of the syphilis study in Tuskegee, continuing congressional dissatisfaction with the way the Pentagon handled its vaccine distribution during the Gulf War, and the controversy about AZT trials in developing countries.On the HillCongressman Christopher Shays, the moderate Connecticut Republican who has developed an interest in human research issues, convened hearings on human [End Page 329] subjects research and the IRB system on 11 June 1998. Shays chairs the House Government Reform/Human Resources Subcommittee. The committee’s ranking minority member is Edolphus Towns of Brooklyn, NY, who shares Shays’s interest in this area.The immediate rationale for the hearings was the release that day of the DHHS-IG report, Institutional Review Boards: A Time for Reform. The subtitle was changed from A System in Jeopardy apparently after some people in DHHS expressed reservations about its seemingly alarmist tone, but the IG staffers who testified before Shays’s subcommittee insisted that they stood behind the message that the IRB system is in trouble if considerable reforms are not undertaken. Among the factors in the research environment cited as support for the bleak forecast: managed care, commercialization, multi-site trials, high IRB workloads, minimal IRB oversight of approved studies, conflicts of interest, insufficient training of IRB members and investigators, and lack of IRB self-studies (DHHS-IG 1998).As is normally the case for congressional oversight hearings, the first panel of witnesses consisted of executive branch officials, including Eric Meslin, Executive Director of the National Bioethics Advisory Commission, and Gary Ellis, Director of the Office for Protection from Research Risks (OPRR). Shays pressed Ellis on the extent to which OPRR conducts on-site investigations of complaints about abuse of human subjects. Admitting that on-site investigations are rare, Ellis suggested that the agency is inadequately staffed to follow up on complaints as quickly as it might wish. The members of Congress who were present at the hearings generally expressed concern about the DHHS-IG’s findings.The second panel that day, which Shays was unable to attend, set a different tone. Four of the panelists—Paul Appelbaum of the University of Massachusetts at Worcester, Robert Levine of Yale University, Angela Bowen of the Western IRB (a private clinical trials review firm), and I—were invited as authorities on the current condition of the IRB system. Bert Spilker... (shrink)